Manuscript references
The full reference list from the IFS manuscript, underlying every claim on the Framework and Evidence pages.
1
Crisco, J. J., Chu, J. J., & Greenwald, R. M. (2004). An algorithm for estimating acceleration magnitude and impact location using multiple nonorthogonal single-axis accelerometers.
Journal of Biomechanical Engineering, 126(6), 849–854.
doi.org/10.1115/1.1824135
2
Crisco, J. J., Fiore, R., Beckwith, J. G., Chu, J. J., Brolinson, P. G., Duma, S. M., McAllister, T. W., Duhaime, A. C., & Greenwald, R. M. (2010). Frequency and location of head impact exposures in individual collegiate football players.
Journal of Athletic Training, 45(6), 549–559.
doi.org/10.4085/1062-6050-45.6.549
3
Greenwald, R. M., Gwin, J. T., Chu, J. J., & Crisco, J. J. (2008). Head impact severity measures for evaluating mild traumatic brain injury risk exposure.
Neurosurgery, 62(4), 789–798.
doi.org/10.1227/01.neu.0000318162.67472.ad
4
O'Connor, K. L., Rowson, S., Duma, S. M., & Broglio, S. P. (2017). Head-impact-measurement devices: A systematic review.
Journal of Athletic Training, 52(3), 206–227.
doi.org/10.4085/1062-6050.52.2.05
5
Le Flao, E., Siegmund, G. P., & Borotkanics, R. (2022). Head impact research using inertial sensors in sport: A systematic review of methods, demographics, and factors contributing to exposure.
Sports Medicine, 52(3), 481–504.
doi.org/10.1007/s40279-021-01574-y
6
Basinas, I., Sævarsson, S. K., & McCarthy, C. (2022). A systematic review of head impacts and acceleration associated with soccer.
International Journal of Environmental Research and Public Health, 19, 5488.
doi.org/10.3390/ijerph19095488
7
De Sousa-De Sousa, L., Espinosa, H. G., Maté-Muñoz, J. L., García-Manso, J. M., Ara, I., & Manonelles, P. (2025). Unlocking the impact: A systematic review and meta-analysis of biomechanical insights into rugby head impacts using wearable sensor technology.
Sports Medicine, Advance online publication.
doi.org/10.1007/s40279-025-02228-z
8
Tierney, G. (2024). Concussion biomechanics, head acceleration exposure and brain injury criteria in sport: A review.
Sports Biomechanics, 23(11), 1888–1916.
doi.org/10.1080/14763141.2021.2016929
9
King, D., Hume, P., Gissane, C., Brughelli, M., & Clark, T. (2016). The influence of head impact threshold for reporting data in contact and collision sports: Systematic review and original data analysis.
Sports Medicine, 46(2), 151–169.
doi.org/10.1007/s40279-015-0423-7
10
Rowson, S., Bland, M. L., Campolettano, E. T., Press, J. N., Hegeman, G., Dudek, J. E., Rowson, B., & Duma, S. M. (2012). Rotational head kinematics in football impacts: An injury risk function for concussion.
Annals of Biomedical Engineering, 40(1), 1–13.
doi.org/10.1007/s10439-011-0392-4
11
Gabler, L. F., Crandall, J. R., & Panzer, M. B. (2018). Development of a metric for predicting brain strain responses using head kinematics.
Annals of Biomedical Engineering, 46(7), 972–985.
doi.org/10.1007/s10439-018-2015-9
12
Gabler, L. F., Joodaki, H., Crandall, J. R., & Panzer, M. B. (2018). Development of a single-degree-of-freedom mechanical model for predicting strain-based brain injury responses.
Journal of Biomechanical Engineering, 140(3), 031002.
doi.org/10.1115/1.4038357
13
Gabler, L. F., Crandall, J. R., & Panzer, M. B. (2019). Development of a second-order system for rapid estimation of maximum brain strain.
Annals of Biomedical Engineering, 47(9), 1971–1981.
doi.org/10.1007/s10439-019-02213-9
14
Guskiewicz, K. M., Mihalik, J. P., Shankar, V., Marshall, S. W., Crowell, D. H., Oliaro, S. M., Ciocca, M. F., & Hooker, D. N. (2007). Measurement of head impacts in collegiate football players: Relationship between head impact biomechanics and acute clinical outcome after concussion.
Neurosurgery, 61(6), 1244–1253.
doi.org/10.1227/01.neu.0000306103.68635.1a
15
Rowson, S., & Duma, S. M. (2013). Brain injury prediction: Assessing the combined probability of concussion using linear and rotational head acceleration.
Annals of Biomedical Engineering, 41(5), 873–882.
doi.org/10.1007/s10439-012-0731-0
16
Eckner, J. T., Oh, Y. K., Joshi, M. S., Richardson, J. K., & Ashton-Miller, J. A. (2014). Effect of neck muscle strength and anticipatory cervical muscle activation on the kinematic response of the head to impulsive loads.
American Journal of Sports Medicine, 42(3), 566–576.
doi.org/10.1177/0363546513517869
17
Cournoyer, J., Koncan, D., Gilchrist, M. D., & Hoshizaki, T. B. (2021). The influence of neck stiffness on head kinematics and maximum principal strain associated with youth American football collisions.
Journal of Applied Biomechanics, 37(3), 288–295.
doi.org/10.1123/jab.2020-0070
19
Ji, S., Ghadyani, H., Bolander, R. P., Beckwith, J. G., Ford, J. C., McAllister, T. W., Flashman, L. A., Paulsen, K. D., Fehlings, M. G., & Greenwald, R. M. (2014). Parametric comparisons of intracranial mechanical responses from three validated finite element models of the human head.
Annals of Biomedical Engineering, 42(1), 11–24.
doi.org/10.1007/s10439-013-0852-4
20
Zhan, X., Li, Y., Liu, Y., Cecchi, N. J., Raymond, S. J., Zhou, Z., Alizadeh, H. V., Ruan, J., Barbat, S., Tiernan, S., Gevaert, O., Zeineh, M. M., Grant, G. A., & Camarillo, D. B. (2023). Machine-learning-based head impact subtyping based on spectral densities of head kinematics.
Journal of Sport and Health Science, 12(5), 619–629.
doi.org/10.1016/j.jshs.2023.03.003
21
Wu, L. C., Zarnescu, L., Nandigam, V., Cam, B., & Camarillo, D. B. (2016). Kinematic and biomechanical analysis of head impacts in the National Football League.
Annals of Biomedical Engineering, 44(2), 454–462.
doi.org/10.1007/s10439-015-1502-5
22
Camarillo, D. B., Shull, P. B., Mattson, J., Shultz, R., & Garza, D. (2013). An instrumented mouthguard for measuring linear and angular head impact kinematics in American football.
Annals of Biomedical Engineering, 41(9), 1939–1949.
doi.org/10.1007/s10439-013-0801-y
23
Rowson, S., & Duma, S. M. (2022). A review of head injury metrics used in automotive safety and sports protective equipment.
Journal of Biomechanical Engineering, 144(11), 110801.
doi.org/10.1115/1.4054379
24
Joodaki, H., Bailey, A., Lessley, D., Funk, J., Sherwood, C., & Crandall, J. (2019). Relative motion between the helmet and the head in football impact test.
Journal of Biomechanical Engineering, 141(8), 081006.
doi.org/10.1115/1.4043038
25
Jones, B., Tooby, J., Weaving, D., Till, K., Owen, C., Begonia, M., Stokes, K. A., Rowson, S., Phillips, G., Hendricks, S., Falvey, É. C., Al-Dawoud, M., & Tierney, G. (2022). Ready for impact? A validity and feasibility study of instrumented mouthguards (iMGs).
British Journal of Sports Medicine, 56(20), 1171–1179.
doi.org/10.1136/bjsports-2022-105523
26
Sciacca, D., & Ionescu, A. (2025). Helmet–head decoupling in ice hockey impacts: An in-lab exploratory study using autoregressive modeling.
Annals of Biomedical Engineering, 53(11), 3141–3155.
doi.org/10.1007/s10439-025-03848-2
27
Luke, D., Kenny, R., Bondi, D., Clansey, A., & Wu, L. C. (2024). On-field instrumented mouthguard coupling.
Journal of Biomechanics, 162, 111889.
doi.org/10.1016/j.jbiomech.2023.111889
28
Clansey, A. C., Bondi, D., Kenny, R., Luke, D., Masood, Z., Gao, Y., Elez, M., Ji, S., Rauscher, A., van Donkelaar, P., & Wu, L. C. (2024). On-field head acceleration exposure measurements using instrumented mouthguards: Multi-stage screening to optimize data quality.
Annals of Biomedical Engineering, 52(10), 2666–2677.
doi.org/10.1007/s10439-024-03592-z
30
Wisehockey Ltd. (2025).
Wisehockey real-time ice hockey analytics platform.
wisesport.com/hockey. Accessed October 2025.
31
Zhao, W., & Ji, S. (2017). Brain strain uncertainty due to shape variation in and simplification of head angular velocity profiles.
Biomechanics and Modeling in Mechanobiology, 16(2), 449–461.
doi.org/10.1007/s10237-016-0829-7
32
Bain, A. C., & Meaney, D. F. (2000). Tissue-level thresholds for axonal damage in an experimental model of central nervous system white matter injury.
Journal of Biomechanical Engineering, 122(6), 615–622.
doi.org/10.1115/1.1324667
33
Kleiven, S. (2007). Predictors for traumatic brain injuries evaluated through accident reconstructions.
Stapp Car Crash Journal, 51, 81–114.
doi.org/10.4271/2007-22-0003
34
Wang, T., Kenny, R., & Wu, L. C. (2021). Head impact sensor triggering bias introduced by linear acceleration thresholding.
Annals of Biomedical Engineering, 49(12), 3189–3199.
doi.org/10.1007/s10439-021-02868-y
35
McKee, A. C., Stern, R. A., Nowinski, C. J., Stein, T. D., Alvarez, V. E., Daneshvar, D. H., et al. (2013). The spectrum of disease in chronic traumatic encephalopathy.
Brain, 136(Pt 1), 43–64.
doi.org/10.1093/brain/aws307
36
Mainwaring, L., Pennock, K. M. F., Mylabathula, S., & Alavie, B. Z. (2018). Subconcussive head impacts in sport: A systematic review of the evidence.
International Journal of Psychophysiology, 132, 39–54.
doi.org/10.1016/j.ijpsycho.2018.01.007
37
Caccese, J. B., Best, C., Lamond, L. C., DiFabio, M., Kaminski, T. W., Watson, D. A. N., Getchell, N., & Buckley, T. A. (2019). Effects of repetitive head impacts on a concussion assessment battery.
Medicine & Science in Sports & Exercise, 51, 1355–1361.
doi.org/10.1249/MSS.0000000000001905
38
Gabler, L., Patton, D., Begonia, M., Daniel, R., Rezaei, A., Huber, C., Siegmund, G., Rooks, T., & Wu, L. C. (2022). Consensus Head Acceleration Measurement Practices (CHAMP): Laboratory validation of wearable head kinematic devices.
Annals of Biomedical Engineering, 50(11), 1356–1371.
doi.org/10.1007/s10439-022-03066-0
39
Kuo, C., Patton, D., Rooks, T., Tierney, G., McIntosh, A., Lynall, R., Esquivel, A., Daniel, R., Kaminski, T., Mihalik, J., Dau, N., & Urban, J. (2022). On-field deployment and validation for wearable devices.
Annals of Biomedical Engineering, 50(11), 1372–1388.
doi.org/10.1007/s10439-022-03001-3
41
McCrory, P., Meeuwisse, W., Dvořák, J., et al. (2017). Consensus statement on concussion in sport — the 5th international conference on concussion in sport held in Berlin, October 2016.
British Journal of Sports Medicine, 51, 838–847.
doi.org/10.1136/bjsports-2017-097699
42
Wu, L. C., Nangia, V., Bui, K., Hammoor, B., Kurt, M., Hernandez, F., Kuo, C., & Camarillo, D. B. (2016). In vivo evaluation of wearable head impact sensors.
Annals of Biomedical Engineering, 44(4), 1234–1245.
doi.org/10.1007/s10439-015-1423-3
43
Wu, L. C., Kuo, C., Loza, J., Kurt, M., Laksari, K., Yanez, L. Z., Senif, D., Anderson, S. C., Miller, L. E., Urban, J. E., Stitzel, J. D., & Camarillo, D. B. (2018). Detection of American football head impacts using biomechanical features and support vector machine classification.
Scientific Reports, 8, 855.
doi.org/10.1038/s41598-017-17864-3
Supplement references (additional to the above)
The supplementary discussion cites the same literature-positioning sources as the manuscript (Basinas, Beckwith, Camarillo, Kuo, Le Flao, O'Connor, Rowson & Duma, Wu, Zhan, De Sousa-De Sousa — all listed above), plus two additional sources.
44
Beckwith, J. G., Greenwald, R. M., & Chu, J. J. (2012). Measuring head kinematics in football: Correlation between the head impact telemetry system and Hybrid III headform.
Annals of Biomedical Engineering, 40(1), 237–248.
doi.org/10.1007/s10439-011-0422-2
45
Kuo, C., Wu, L., Loza, J., Senif, D., Anderson, S. C., & Camarillo, D. B. (2018). Comparison of video-based and sensor-based head impact exposure.
PLoS ONE, 13(6), e0199238.
doi.org/10.1371/journal.pone.0199238
Historical sources (The Story)
The primary and archival sources behind the timeline on The Story. Two of these (Holbourn 1943 and Rowson et al. 2012) are the same works cited as [10] and [40] above.
47
Ommaya, A. K., Hirsch, A. E., Flamm, E. S., & Mahone, R. H. (1966). Cerebral concussion in the monkey: An experimental model. Science, 153(3732), 211–212.
48
Gennarelli, T. A., Thibault, L. E., & Ommaya, A. K. (1972). Pathophysiologic responses to rotational and translational accelerations of the head. In Proceedings of the 16th Stapp Car Crash Conference (SAE Technical Paper 720970).
49
Ommaya, A. K., & Gennarelli, T. A. (1974). Cerebral concussion and traumatic unconsciousness: Correlation of experimental and clinical observations of blunt head injuries. Brain, 97(4), 633–654.
50
Gennarelli, T. A., Thibault, L. E., Adams, J. H., Graham, D. I., Thompson, C. J., & Marcincin, R. P. (1982). Diffuse axonal injury and traumatic coma in the primate. Annals of Neurology, 12(6), 564–574.
51
Versace, J. (1971). A review of the severity index. In Proceedings of the 15th Stapp Car Crash Conference (SAE Technical Paper 710881).
52
Rowson, S., Bland, M. L., Campolettano, E. T., Press, J. N., Hegeman, G., Dudek, J. E., Rowson, B., & Duma, S. M. (2012). Rotational head kinematics in football impacts: An injury risk function for concussion.
Annals of Biomedical Engineering, 40(1), 1–13.
doi.org/10.1007/s10439-011-0392-4
53
Kimpara, H., Nakahira, Y., Iwamoto, M., Rowson, S., & Duma, S. (2011). Head injury prediction methods based on 6 degree of freedom head acceleration measurements during impact.
International Journal of Automotive Engineering, 2(2), 13–19.
doi.org/10.20485/jsaeijae.2.2_13
54
Takhounts, E. G., Craig, M. J., Moorhouse, K., McFadden, J., & Hasija, V. (2013). Development of Brain Injury Criteria (BrIC). Stapp Car Crash Journal, 57, 243–266.
Chronic head-impact injury, historical background
The two sources behind the historical background on Applications — the first clinical description of chronic head-impact injury in boxing, and the first description of the same disease process, under its modern name, in an American football player.
56
Omalu, B. I., DeKosky, S. T., Minster, R. L., Kamboh, M. I., Hamilton, R. L., & Wecht, C. H. (2005). Chronic traumatic encephalopathy in a National Football League player.
Neurosurgery, 57(1), 128–134.
doi.org/10.1227/01.neu.0000163407.92769.ed